Pure Primary Extragonadal Yolk Sac Tumor involving stomach in a Young Child: A Case Report

  • Faisal R Guru Department of Paediatric Oncology Sher I Kashmir Of Medical Sciences
  • Saquib Zaffar DM Scholar Medical Oncology Sher I Kashmir Institute Of Medical sciences
  • Huma Noor DM Scholar Medical Oncology Sher I Kashmir Institute Of Medical sciences
  • Salma Gull PG Scholar Pathology Sher I Kashmir Institute Of Medical sciences
  • Gull Muhammad Bhat Department of Medical Oncology SKIMS
Keywords: Extragonadal Yolk Sac

Abstract

Germ Cell Tumors (GCTs)  constitute approximately only 3% of all malignancies in children younger than 15 years of age. Primary extragonadal GCTs constitute only 1-5% of all GCTs and a retroperitoneal site is seen only in 4% of all extragonadal GCTs. Yolk sac tumor is the predominant variant in newborns and younger children. GCTs of stomach are very very rare.We report for the first time, the presentation of a primary yolk sac tumor arising from the stomach of a small child.

 

Author Biographies

Faisal R Guru, Department of Paediatric Oncology Sher I Kashmir Of Medical Sciences

Assistant Professor

Gull Muhammad Bhat, Department of Medical Oncology SKIMS

M.D., Professor 

References

[1] Gobel U, Schneider DT, Calaminus G, Haas RJ, Schmidt P, Harms D. Germ cell tumors in childhood and adolescence. GPOH MAKEI and the MAHO study groups. Ann Oncol. 2000; 11(3):263-71.
[2] Deb M, Mohanty S, Ananthamurthy A, Garg I, Das K. Atypical extragonadal germ cell tumors. J Indian Assoc Pediatric Surg. 2012; 17:9-15.
[3] Eble J. Pathology and genetics of tumors of the urinary system and male genital organs. Lyon: IARC Press; 2004; Pp. 237-40.
[4] Horton Z, Schlatter M, Schultz S. Pediatric germ cell tumors. Surg Oncol. 2007; 16(3):205-13.
[5] Dede M, Pabuccu R, Yagci G, Yenen M, Goktolga U, Gunhan O. Extragonadal yolk sac tumor in pelvic localization. A case report and literature review. Gynecol Oncol. 2004; 92(3):989-91.
[6] Shinagare A, Jagannathan J, Ramaiya N, Hall M, Van den Abbeele A. Adult extragonadal germ cell tumors. AJR Am J Roentgenol. 2010; 195(4):W274- W280.
[7] Albany C, Einhorn LH. Extragonadal germ cell tumors: clinical presentation and management. CurrOpin Oncol. 2013; 25:261–65.
[8] Arumugam D, Thandavarayan P, Chidambaram L, Boj S, Marudasalam S. Primary nasopharngeal yolk sac tumor: A case report. JCDR. 2016; 10(5):6-7.
[9] Dabbs D. Diagnostic immunohistochemistry. 3rd ed. Philadelphia, PA: Saunders/ Elsevier; 2010; Pp.737-739.
[10] Roth L, Panganiban W. Gonadal and extragonadal yolk sac carcinomas. A clinicopathologic study of 14 cases. Cancer. 1976; 37(2):812-20.
[11] Brodeur G, Howarth C, Pratt C, Caces J, Hustu H. Malignant germ cell tumors in 57 children and adolescents. Cancer. 1981; 48(8):1890-98.
[12] Lack E, Travis W, Welch K. Retroperitoneal germ cell tumors in childhood. A clinical and pathologic study of 11 cases. Cancer. 1985; 56(3):602-08.
[13] Agarwal BR, Patel M, Shah BN, Currimbhoy Z, Waingankar VS, Meisheri I, et al. Endodermal sinus tumor: report of 12 cases. Indian Pediatric. 1993; 30:1321-25.
[14] Murat E, Dagdemir A, Bilgici M, Sullu Y. Primary yolk sac tumor of the retroperitoneal region. Contemp Onco . 2013; 17(6):530–32.
[15] Choudaha P, Likhar KS, Gupta SG, Patle Y, Hazari RA. Extragonadal retroperitoneal pure yolk sac tumour. PJSR. 2014:7(2):47-50.
[16] Nisar A Bhat, Aftab S. Chishti et.al Gastric immature Teratoma Saudi Med J 2007:Vol 2.28(6).
[17]. Shakeel A Malik, Nisar A. Bhat et. Al Malignant gastric Teratoma – A Case Report. JK Practitioner. Vol.5 No.2, April –June 1998.
Published
2019-05-27
How to Cite
1.
Guru FR, Zaffar S, Noor H, Gull S, Bhat GM. Pure Primary Extragonadal Yolk Sac Tumor involving stomach in a Young Child: A Case Report. jms [Internet]. 2019May27 [cited 2019Jul.19];22(1):75-7. Available from: http://jmsskims.org/index.php/jms/article/view/396
Section
Case Reports