Vitamin D supplementation –Is it the time to stop wasting money on vitamin D?

  • Shariq Rashid Masoodi Department of Endocrinology SKIMS
Keywords: Vitamin D

Abstract

In recent years, vitamin D has received increased attention, as a number of studies have shown its link to the pathogenesis of various diseases. Apart from its benefits on bone health, vitamin D supplementation has been shown beneficial in reducing risk for many chronic diseases including autoimmune diseases, type 2 diabetes, heart disease, many cancers and infectious diseases. Vitamin deficiency has been associated with increased risk of elevated blood pressure, heart attack and stroke in studies. The relationship between vitamin D deficiency and the increased incidence of upper respiratory infections, asthma and eczema, among children, has been observed in several studies. Recent meta-analyzes showed a relationship between vitamin D administration during the early months of life and a lower incidence of type 1 diabetes later in life. Therefore, it is not surprising that Vitamin D supplementation is used to prevent and treat a wide range of diseases, and the use has increased considerably in the last decade.

References

Ross AC, Taylor CL, Yaktine AL, Del Valle HB, eds.; Institute of Medicine (U.S.) Committee. Dietary reference intakes for calcium and vitamin D. Washington DC: National Academies Press, 2011.
2. Bolland MJ, Grey A, Avenell A. Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis. lancet Diabetes Endocrinol 2018;6(11):847–58.
3. Avenell A, Mak JC, O’Connell D. Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men. Cochrane Database Syst Rev 2014;(4).
4. Grossman DC, Curry SJ, Owens DK, et al. Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults. JAMA 2018;319(15):1592.
5. Manson JE, Cook NR, Lee I-M, et al. Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease. N Engl J Med 2019;380(1):33–44.
6. Keum N, Giovannucci E. Vitamin D supplements and cancer incidence and mortality: a meta-analysis. Br J Cancer 2014;111(5):976–80.
7. McCullough ML, Zoltick ES, Weinstein SJ, et al. Circulating Vitamin D and Colorectal Cancer Risk: An International Pooling Project of 17 Cohorts. JNCI J Natl Cancer Inst 2019;111(2):158–69.
8. Wu K, Willett WC, Fuchs CS, Colditz GA, Giovannucci EL. Calcium intake and risk of colon cancer in women and men. J Natl Cancer Inst 2002;94(6):437–46.
Published
2019-03-29
How to Cite
1.
Masoodi SR. Vitamin D supplementation –Is it the time to stop wasting money on vitamin D?. jms [Internet]. 2019Mar.29 [cited 2019Jun.25];22(1):1-. Available from: http://jmsskims.org/index.php/jms/article/view/442
Section
Editorial